NEW YORK (Reuters Health) - Nearly one in ten U.S. children undergoing spine fusion surgery get injections with bioengineered bone-growth proteins that have not been green-lighted for that use by health regulators, researchers have found. So-called "off-label" use of medical therapies is legal, but has triggered concerns because its risks and benefits are not well understood. Yet the new study shows the orthopedic products add more than $4,000 in hospital charges for the surgery. "It is expensive, we don't know if it's effective, and we don't know what the long-term implications are," said Dr. ... Credit of the story
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